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The effects of long-term daily folic acid and vitamin B(12) supplementation on genome-wide DNA methylation in elderly subjects
BACKGROUND: Folate and its synthetic form folic acid function as donor of one-carbon units and have been, together with other B-vitamins, implicated in programming of epigenetic processes such as DNA methylation during early development. To what extent regulation of DNA methylation can be altered vi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644301/ https://www.ncbi.nlm.nih.gov/pubmed/26568774 http://dx.doi.org/10.1186/s13148-015-0154-5 |