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The effects of long-term daily folic acid and vitamin B(12) supplementation on genome-wide DNA methylation in elderly subjects

BACKGROUND: Folate and its synthetic form folic acid function as donor of one-carbon units and have been, together with other B-vitamins, implicated in programming of epigenetic processes such as DNA methylation during early development. To what extent regulation of DNA methylation can be altered vi...

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Detalles Bibliográficos
Autores principales:	Kok, Dieuwertje E. G., Dhonukshe-Rutten, Rosalie A. M., Lute, Carolien, Heil, Sandra G., Uitterlinden, André G., van der Velde, Nathalie, van Meurs, Joyce B. J., van Schoor, Natasja M., Hooiveld, Guido J. E. J., de Groot, Lisette C. P. G. M., Kampman, Ellen, Steegenga, Wilma T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644301/ https://www.ncbi.nlm.nih.gov/pubmed/26568774 http://dx.doi.org/10.1186/s13148-015-0154-5

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