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Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells

BACKGROUND: Duchenne muscular dystrophy (DMD) is a devastating X-linked recessive genetic myopathy. DMD physiopathology is still not fully understood and a prenatal onset is suspected but difficult to address. METHODS: The bone morphogenetic protein 4 (BMP4) is a critical signaling molecule involved...

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Detalles Bibliográficos
Autores principales: Massouridès, Emmanuelle, Polentes, Jérôme, Mangeot, Philippe-Emmanuel, Mournetas, Virginie, Nectoux, Juliette, Deburgrave, Nathalie, Nusbaum, Patrick, Leturcq, France, Popplewell, Linda, Dickson, George, Wein, Nicolas, Flanigan, Kevin M., Peschanski, Marc, Chelly, Jamel, Pinset, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644319/
https://www.ncbi.nlm.nih.gov/pubmed/26568816
http://dx.doi.org/10.1186/s13395-015-0062-6