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Origin and interpretation of cancer transcriptome profiling: the essential role of the stroma in determining prognosis and drug resistance
Mesenchymal gene expression in tumors has been implicated in cancer recurrence, metastasis, and poor prognosis of patients. The source of these mesenchymal signals has been mostly attributed to the epithelial-to-mesenchymal transition-like phenotype of epithelial tumor cells. However, recent evidenc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644372/ https://www.ncbi.nlm.nih.gov/pubmed/26240076 http://dx.doi.org/10.15252/emmm.201505284 |