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Origin and interpretation of cancer transcriptome profiling: the essential role of the stroma in determining prognosis and drug resistance

Mesenchymal gene expression in tumors has been implicated in cancer recurrence, metastasis, and poor prognosis of patients. The source of these mesenchymal signals has been mostly attributed to the epithelial-to-mesenchymal transition-like phenotype of epithelial tumor cells. However, recent evidenc...

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Detalles Bibliográficos
Autores principales: Goossens, Nicolas, Hoshida, Yujin, Aguirre-Ghiso, Julio A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644372/
https://www.ncbi.nlm.nih.gov/pubmed/26240076
http://dx.doi.org/10.15252/emmm.201505284