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Defective autophagy is a key feature of cerebral cavernous malformations

Cerebral cavernous malformation (CCM) is a major cerebrovascular disease affecting approximately 0.3–0.5% of the population and is characterized by enlarged and leaky capillaries that predispose to seizures, focal neurological deficits, and fatal intracerebral hemorrhages. Cerebral cavernous malform...

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Detalles Bibliográficos
Autores principales: Marchi, Saverio, Corricelli, Mariangela, Trapani, Eliana, Bravi, Luca, Pittaro, Alessandra, Delle Monache, Simona, Ferroni, Letizia, Patergnani, Simone, Missiroli, Sonia, Goitre, Luca, Trabalzini, Lorenza, Rimessi, Alessandro, Giorgi, Carlotta, Zavan, Barbara, Cassoni, Paola, Dejana, Elisabetta, Retta, Saverio Francesco, Pinton, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644374/
https://www.ncbi.nlm.nih.gov/pubmed/26417067
http://dx.doi.org/10.15252/emmm.201505316