Isoflurane Damages the Developing Brain of Mice and Induces Subsequent Learning and Memory Deficits through FASL-FAS Signaling

Background. Isoflurane disrupts brain development of neonatal mice, but its mechanism is unclear. We explored whether isoflurane damaged developing hippocampi through FASL-FAS signaling pathway, which is a well-known pathway of apoptosis. Method. Wild type and FAS- or FASL-gene-knockout mice aged 7...

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Detalles Bibliográficos
Autores principales: Yi, Xiuwen, Cai, Yirong, Li, Wenxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644536/
https://www.ncbi.nlm.nih.gov/pubmed/26609525
http://dx.doi.org/10.1155/2015/315872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644536/
https://www.ncbi.nlm.nih.gov/pubmed/26609525
http://dx.doi.org/10.1155/2015/315872

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