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A Novel Nitronyl Nitroxide with Salicylic Acid Framework Attenuates Pain Hypersensitivity and Ectopic Neuronal Discharges in Radicular Low Back Pain

Evidence has accumulated that reactive oxygen species and inflammation play crucial roles in the development of chronic pain, including radicular low back pain. Nonsteroid anti-inflammatory drugs (NSAIDs), for example, salicylic acid, aspirin, provided analgesic effects in various types of pain. How...

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Detalles Bibliográficos
Autores principales: Han, Wen-Juan, Chen, Lei, Wang, Hai-Bo, Liu, Xiang-Zeng, Hu, San-Jue, Sun, Xiao-Li, Luo, Ceng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644553/
https://www.ncbi.nlm.nih.gov/pubmed/26609438
http://dx.doi.org/10.1155/2015/752782