Double Heterozygosity of BRCA2 and STK11 in Familial Breast Cancer Detected by Exome Sequencing

BACKGROUND: Germ-line mutations of BRCA1 and BRCA2 genes are responsible for approximately 25–30% of dominantly inherited familial breast cancers; still a big part of genetic component is unknown. The aim of this study was to investigate genetic causes of familial breast cancer in a pedigree with re...

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Detalles Bibliográficos
Autores principales: ATAEI-KACHOUEI, Mojgan, NADAF, Javad, AKBARI, Mohammad Taghi, ATRI, Morteza, MAJEWSKI, Jacek, RIAZALHOSSEINI, Yasser, GARSHASBI, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644579/
https://www.ncbi.nlm.nih.gov/pubmed/26576347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644579/
https://www.ncbi.nlm.nih.gov/pubmed/26576347

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