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The Role of Oxidized Cholesterol in Diabetes-Induced Lysosomal Dysfunction in the Brain

Abnormalities in lysosomal function have been reported in diabetes, aging, and age-related degenerative diseases. These lysosomal abnormalities are an early manifestation of neurodegenerative diseases and often precede the onset of clinical symptoms such as learning and memory deficits; however, the...

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Detalles Bibliográficos
Autores principales: Sims-Robinson, Catrina, Bakeman, Anna, Rosko, Andrew, Glasser, Rebecca, Feldman, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644712/
https://www.ncbi.nlm.nih.gov/pubmed/25976368
http://dx.doi.org/10.1007/s12035-015-9207-1