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The Role and Mechanism of α-Klotho in the Calcification of Rat Aortic Vascular Smooth Muscle Cells

Objective. To investigate the role and possible mechanism of α-Klotho in the calcification and the osteogenic transition of cultured VSMCs. Methods. VSMCs were cultured in vitro and divided into 5 groups, each using a different medium: (1) control; (2) β-GP; (3) β-GP + Klotho; (4) β-GP + LiCl; (5) β...

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Detalles Bibliográficos
Autores principales: Chen, Tianlei, Mao, Huijuan, Chen, Cheng, Wu, Lin, Wang, Ningning, Zhao, Xiufen, Qian, Jun, Xing, Changying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644825/
https://www.ncbi.nlm.nih.gov/pubmed/26609522
http://dx.doi.org/10.1155/2015/194362