Cargando…

Tetrathiomolybdate mediates cisplatin-induced p38 signaling and EGFR degradation and enhances response to cisplatin therapy in gynecologic cancers

Cisplatin and its analogs are among the most widely used chemotherapeutic agents against various types of cancer. It is known that cisplatin can activate epidermal growth factor receptor (EGFR), which may provide a survival benefit in cancers. Tetrathiomolybdate (TM) is a potent anti-cancer and anti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Kyu Kwang, Han, Alex, Yano, Naohiro, Ribeiro, Jennifer R., Lokich, Elizabeth, Singh, Rakesh K., Moore, Richard G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644948/ https://www.ncbi.nlm.nih.gov/pubmed/26568478 http://dx.doi.org/10.1038/srep15911

Ejemplares similares

Tetrathiomolybdate inhibits mitochondrial complex IV and mediates degradation of hypoxia-inducible factor-1α in cancer cells
por: Kwang Kim, Kyu, et al.
Publicado: (2015)

Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin
por: Chisholm, Cristine L., et al.
Publicado: (2016)

Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C
por: Kim, Kyu Kwang, et al.
Publicado: (2012)

HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocation
por: Lokich, Elizabeth, et al.
Publicado: (2014)

Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway
por: Qi, Hao, et al.
Publicado: (2023)

Ammonium tetrathiomolybdate enhances the antitumor effect of cisplatin via the suppression of ATPase copper transporting beta in head and neck squamous cell carcinoma
por: Ryumon, Shoji, et al.
Publicado: (2019)

Novel Small Molecule MEK Inhibitor URML-3881 Enhances Cisplatin Sensitivity in Clear Cell Ovarian Cancer
por: Rowswell-Turner, Rachael B., et al.
Publicado: (2019)

Synergistic Enhancement of Cisplatin Cytotoxicity by SN‐38, an Active Metabolite of CPT‐11, for Cisplatin‐resistant HeLa Cells
por: Minagawa, Yukihisa, et al.
Publicado: (1994)

Metformin combined with p38 MAPK inhibitor improves cisplatin sensitivity in cisplatin-resistant ovarian cancer
por: XIE, YA, et al.
Publicado: (2014)

Ammonium tetrathiomolybdate treatment of copper‐associated hepatopathy in dogs
por: Langlois, Daniel K., et al.
Publicado: (2019)

HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells
por: Ribeiro, J. R., et al.
Publicado: (2016)

Paclitaxel and SN‐38 Overcome Cisplatin Resistance of Ovarian Cancer Cell Lines by Down‐regulating the Influx and Efflux System of Cisplatin
por: Komuro, Yuuki, et al.
Publicado: (2001)

EGFR Inhibitor Enhances Cisplatin Sensitivity of Oral Squamous Cell Carcinoma Cell Lines
por: Hiraishi, Yukihiro, et al.
Publicado: (2008)

The EGFR Inhibitor Gefitinib Enhanced the Response of Human Oral Squamous Cell Carcinoma to Cisplatin In Vitro
por: Khalil, Ashraf, et al.
Publicado: (2017)

EGFR Blockade Reverses Cisplatin Resistance in Human Epithelial Ovarian Cancer Cells
por: Poursheikhani, Arash, et al.
Publicado: (2020)

Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein
por: Fang, Tiantian, et al.
Publicado: (2019)

Selective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate
por: Navrátilová, Jarmila, et al.
Publicado: (2017)

Is Hydrogen Sulfide a Concern During Treatment of Lung Adenocarcinoma With Ammonium Tetrathiomolybdate?
por: Li, Xiang, et al.
Publicado: (2020)

Bis-choline tetrathiomolybdate prevents copper-induced blood–brain barrier damage
por: Borchard, Sabine, et al.
Publicado: (2021)

Combination therapy with cisplatin and nifedipine induces apoptosis in cisplatin-sensitive and cisplatin-resistant human glioblastoma cells.
por: Kondo, S., et al.
Publicado: (1995)

MKP-1 suppresses PARP-1 degradation to mediate cisplatin resistance
por: Wang, Juan, et al.
Publicado: (2017)

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway
por: Oh, Se Jin, et al.
Publicado: (2023)

Cisplatin bioconjugated enzymatic GNPs amplify the effect of cisplatin with acquiescence
por: Iram, Sana, et al.
Publicado: (2019)

Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism
por: Karwaciak, Iwona, et al.
Publicado: (2021)

Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-associated cachexia in rats
por: Omoto, Atsushi, et al.
Publicado: (2005)

Ammonium tetrathiomolybdate triggers autophagy-dependent NRF2 activation in vascular endothelial cells
por: Zhang, Mengling, et al.
Publicado: (2022)

Sodium butyrate enhances the cytotoxic effect of cisplatin by abrogating the cisplatin imposed cell cycle arrest
por: Koprinarova, Miglena, et al.
Publicado: (2010)

Co-Delivery of Curcumin and Cisplatin to Enhance Cytotoxicity of Cisplatin Using Lipid-Chitosan Hybrid Nanoparticles
por: Khan, Muhammad Muzamil, et al.
Publicado: (2020)

Thioridazine Enhances Cisplatin-Induced DNA Damage in Cisplatin-Resistant Human Lung Cancer Cells
por: Luo, Yuanyuan, et al.
Publicado: (2022)

Cisplatin-resistant HepG2 cell-derived exosomes transfer cisplatin resistance to cisplatin-sensitive cells in HCC
por: Tang, Zuxiong, et al.
Publicado: (2021)

Active Efflux System for Cisplatin in Cisplatin‐resistant Human KB Cells
por: Fujii, Ryu‐ichi, et al.
Publicado: (1994)

Neuroprotective effects of ammonium tetrathiomolybdate, a slow-release sulfide donor, in a rodent model of regional stroke
por: Mendonça, Bruna Pescador, et al.
Publicado: (2020)

Calponin Expression in Renal Tubulointerstitial Fibrosis Induced in Rats by Cisplatin
por: Yuasa, Takahiro, et al.
Publicado: (2014)

A Dose-Finding Trial for Hyperthermic Intraperitoneal Cisplatin in Gynecological Cancer Patients Receiving Hyperthermic Intraperitoneal Chemotherapy
por: Chan, Chui-ying, et al.
Publicado: (2021)

Ammonium tetrathiomolybdate in the decoppering phase treatment of Wilson's disease with neurological symptoms: A case series
por: De Fabregues, Oriol, et al.
Publicado: (2020)

Tetrathiomolybdate Decreases the Expression of Alkaline Phosphatase in Dermal Papilla Cells by Increasing Mitochondrial ROS Production
por: Li, Fan, et al.
Publicado: (2023)

The copper chelator ammonium tetrathiomolybdate inhibits the progression of experimental endometriosis in TNFR1-deficient mice
por: Conforti, Rocío Ayelem, et al.
Publicado: (2023)

CD44 inhibition attenuates EGFR signaling and enhances cisplatin sensitivity in human EGFR wild-type non-small-cell lung cancer cells
por: Yin, Jianhua, et al.
Publicado: (2020)

Cisplatin in breast cancer.
por: Willemse, P., et al.
Publicado: (1993)

Tirapazamine-cisplatin: the synergy.
por: Gatzemeier, U., et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_j8buaaj6o4vl802lpeid7stb9k