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Co-Expression Network Models Suggest that Stress Increases Tolerance to Mutations

Network models are a well established tool for studying the robustness of complex systems, including modelling the effect of loss of function mutations in protein interaction networks. Past work has concentrated on average damage caused by random node removal, with little attention to the shape of t...

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Detalles Bibliográficos
Autores principales: Lehtinen, Sonja, Bähler, Jürg, Orengo, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644955/
https://www.ncbi.nlm.nih.gov/pubmed/26568486
http://dx.doi.org/10.1038/srep16726