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Cardiac Optogenetics: Enhancement by All-trans-Retinal

All-trans-Retinal (ATR) is a photosensitizer, serving as the chromophore for depolarizing and hyperpolarizing light-sensitive ion channels and pumps (opsins), recently employed as fast optical actuators. In mammalian optogenetic applications (in brain and heart), endogenous ATR availability is not c...

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Detalles Bibliográficos
Autores principales: Yu, Jinzhu, Chen, Kay, Lucero, Rachel V., Ambrosi, Christina M., Entcheva, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644984/
https://www.ncbi.nlm.nih.gov/pubmed/26568132
http://dx.doi.org/10.1038/srep16542