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The second virial coefficient as a predictor of protein aggregation propensity: A self-interaction chromatography study
The second osmotic virial coefficients (b(2)) of four proteins – lysozyme, recombinant human lactoferrin, concanavalin A and catalase were measured by self-interaction chromatography (SIC) in solutions of varying salt type, concentration and pH. Protein aggregate sizes based on the initial hydrodyna...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644993/ https://www.ncbi.nlm.nih.gov/pubmed/26259782 http://dx.doi.org/10.1016/j.ejpb.2015.07.025 |