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Improved anti-glioblastoma efficacy by IL-13Rα2 mediated copolymer nanoparticles loaded with paclitaxel

Glioma presents one of the most malignant brain tumors, and the therapeutic effect is often limited due to the existence of brain tumor barrier. Based on interleukin-13 receptor α2 (IL-13Rα2) over-expression on glioma cell, it was demonstrated to be a potential receptor for glioma targeting. In this...

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Detalles Bibliográficos
Autores principales: Wang, Baoyan, Lv, Lingyan, Wang, Zhi, Jiang, Yan, Lv, Wei, Liu, Xin, Wang, Zhongyuan, Zhao, Yue, Xin, Hongliang, Xu, Qunwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645113/
https://www.ncbi.nlm.nih.gov/pubmed/26567528
http://dx.doi.org/10.1038/srep16589