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miR-34a screened by miRNA profiling negatively regulates Wnt/β-catenin signaling pathway in Aflatoxin B1 induced hepatotoxicity

Aflatoxin-B1 (AFB1), a hepatocarcinogenic mycotoxin, was demonstrated to induce the high rate of hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) participate in the regulation of several biological processes in HCC. However, the function of miRNAs in AFB1-induced HCC has received a little attentio...

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Detalles Bibliográficos
Autores principales: Zhu, Liye, Gao, Jing, Huang, Kunlun, Luo, Yunbo, Zhang, Boyang, Xu, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645126/
https://www.ncbi.nlm.nih.gov/pubmed/26567713
http://dx.doi.org/10.1038/srep16732