Spontaneous membrane-translocating peptides: influence of peptide self-aggregation and cargo polarity

Peptides that translocate spontaneously across cell membranes could transform the field of drug delivery by enabling the transport of otherwise membrane-impermeant molecules into cells. In this regard, a 9-aminoacid-long motif (representative sequence: PLIYLRLLR, hereafter Translocating Motif 9, TM9...

Descripción completa

Detalles Bibliográficos
Autores principales: Macchi, Sara, Signore, Giovanni, Boccardi, Claudia, Di Rienzo, Carmine, Beltram, Fabio, Cardarelli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645181/
https://www.ncbi.nlm.nih.gov/pubmed/26567719
http://dx.doi.org/10.1038/srep16914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645181/
https://www.ncbi.nlm.nih.gov/pubmed/26567719
http://dx.doi.org/10.1038/srep16914

Ejemplares similares