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Spontaneous membrane-translocating peptides: influence of peptide self-aggregation and cargo polarity

Peptides that translocate spontaneously across cell membranes could transform the field of drug delivery by enabling the transport of otherwise membrane-impermeant molecules into cells. In this regard, a 9-aminoacid-long motif (representative sequence: PLIYLRLLR, hereafter Translocating Motif 9, TM9...

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Detalles Bibliográficos
Autores principales:	Macchi, Sara, Signore, Giovanni, Boccardi, Claudia, Di Rienzo, Carmine, Beltram, Fabio, Cardarelli, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645181/ https://www.ncbi.nlm.nih.gov/pubmed/26567719 http://dx.doi.org/10.1038/srep16914

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