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FOXO1 inhibits osteoclastogenesis partially by antagnozing MYC

FOXO transcription factors especially FOXO1 have profound roles in bone development and remodeling. The regulation of cells of the osteoblast lineage by FOXOs is suggested to be stage-specific or context dependent. Intriguingly, recent studies on the role played by FOXOs in osteoclastogenesis reache...

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Detalles Bibliográficos
Autores principales: Tan, Peng, Guan, Hanfeng, Xie, Linka, Mi, Baoguo, Fang, Zhong, Li, Jing, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645183/
https://www.ncbi.nlm.nih.gov/pubmed/26568463
http://dx.doi.org/10.1038/srep16835