Mutational Disruption of cis-Acting Replication Element 2C in Coxsackievirus B3 Leads to 5′-Terminal Genomic Deletions

Following natural human or experimental murine infections and in cell culture, coxsackievirus B (CVB) RNA can persist for weeks in the absence of a cytopathic effect, yet viral RNA remains detectable. Our earlier studies demonstrated that this persistence produced viral RNA with up to 49 nucleotide...

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Detalles Bibliográficos
Autores principales: Smithee, S., Tracy, S., Chapman, N. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645312/
https://www.ncbi.nlm.nih.gov/pubmed/26355088
http://dx.doi.org/10.1128/JVI.01308-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645312/
https://www.ncbi.nlm.nih.gov/pubmed/26355088
http://dx.doi.org/10.1128/JVI.01308-15

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