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Pathophysiological Changes Induced by Pseudomonas aeruginosa Infection Are Involved in MMP-12 and MMP-13 Upregulation in Human Carcinoma Epithelial Cells and a Pneumonia Mouse Model

Pseudomonas aeruginosa infections persist in patients with cystic fibrosis (CF) and drive lung disease progression. P. aeruginosa potently activates the innate immune system mostly through the recognition of pathogen-associated molecular patterns, such as flagellin. Matrix metalloproteinases 12 and...

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Detalles Bibliográficos
Autores principales: Park, Ji-Won, Shin, In-Sik, Ha, Un-Hwan, Oh, Sei-Ryang, Kim, Jae-Hong, Ahn, Kyung-Seop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645383/
https://www.ncbi.nlm.nih.gov/pubmed/26438797
http://dx.doi.org/10.1128/IAI.00619-15