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Pathophysiological Changes Induced by Pseudomonas aeruginosa Infection Are Involved in MMP-12 and MMP-13 Upregulation in Human Carcinoma Epithelial Cells and a Pneumonia Mouse Model
Pseudomonas aeruginosa infections persist in patients with cystic fibrosis (CF) and drive lung disease progression. P. aeruginosa potently activates the innate immune system mostly through the recognition of pathogen-associated molecular patterns, such as flagellin. Matrix metalloproteinases 12 and...
Autores principales: | Park, Ji-Won, Shin, In-Sik, Ha, Un-Hwan, Oh, Sei-Ryang, Kim, Jae-Hong, Ahn, Kyung-Seop |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645383/ https://www.ncbi.nlm.nih.gov/pubmed/26438797 http://dx.doi.org/10.1128/IAI.00619-15 |
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