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Increased food intake with oxyntomodulin analogues

Oxyntomodulin analogues offer a novel treatment for obesity. However during analogue screening in a rat model increased food intake was consistently observed. To further investigate this finding, a series of representative analogues (OXM14 and OXM15) and their Glu-3 equivalents (OXM14E3 and OXM15E3)...

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Detalles Bibliográficos
Autores principales: Price, Samantha L., Minnion, James S., Bloom, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645461/
https://www.ncbi.nlm.nih.gov/pubmed/26431789
http://dx.doi.org/10.1016/j.peptides.2015.09.006