Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion

To date, the majority of work on RNA virus replication fidelity has focused on the viral RNA polymerase, while the potential role of other viral replicase proteins in this process is poorly understood. Previous studies used resistance to broad-spectrum RNA mutagens, such as ribavirin, to identify po...

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Detalles Bibliográficos
Autores principales: Stapleford, Kenneth A., Rozen-Gagnon, Kathryn, Das, Pratyush Kumar, Saul, Sirle, Poirier, Enzo Z., Blanc, Hervé, Vidalain, Pierre-Olivier, Merits, Andres, Vignuzzi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645662/
https://www.ncbi.nlm.nih.gov/pubmed/26311883
http://dx.doi.org/10.1128/JVI.01553-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645662/
https://www.ncbi.nlm.nih.gov/pubmed/26311883
http://dx.doi.org/10.1128/JVI.01553-15

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