Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR

Streptococcus pneumoniae is an important human pathogen that causes a range of disease states. Sialidases are important bacterial virulence factors. There are three pneumococcal sialidases: NanA, NanB, and NanC. NanC is an unusual sialidase in that its primary reaction product is 2-deoxy-2,3-didehyd...

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Detalles Bibliográficos
Autores principales: Owen, C. David, Lukacik, Petra, Potter, Jane A., Sleator, Olivia, Taylor, Garry L., Walsh, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646021/
https://www.ncbi.nlm.nih.gov/pubmed/26370075
http://dx.doi.org/10.1074/jbc.M115.673632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646021/
https://www.ncbi.nlm.nih.gov/pubmed/26370075
http://dx.doi.org/10.1074/jbc.M115.673632

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