X-ray Structural and Functional Studies of the Three Tandemly Linked Domains of Non-structural Protein 3 (nsp3) from Murine Hepatitis Virus Reveal Conserved Functions

Murine hepatitis virus (MHV) has long served as a model system for the study of coronaviruses. Non-structural protein 3 (nsp3) is the largest nsp in the coronavirus genome, and it contains multiple functional domains that are required for coronavirus replication. Despite the numerous functional stud...

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Detalles Bibliográficos
Autores principales: Chen, Yafang, Savinov, Sergey N., Mielech, Anna M., Cao, Thu, Baker, Susan C., Mesecar, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646180/
https://www.ncbi.nlm.nih.gov/pubmed/26296883
http://dx.doi.org/10.1074/jbc.M115.662130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646180/
https://www.ncbi.nlm.nih.gov/pubmed/26296883
http://dx.doi.org/10.1074/jbc.M115.662130

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