Hepatocyte-Specific Arid1a Deficiency Initiates Mouse Steatohepatitis and Hepatocellular Carcinoma

ARID1A, encoding a subunit of chromatin remodeling SWI/SNF complexes, has recently been considered as a new type of tumor suppressor gene for its somatic mutations frequently found in various human tumors, including hepatocellular carcinoma (HCC). However, the role and mechanism of inactivated ARID1...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Jia-Zhu, Li, Chong, Liu, Xiao-Yan, Hu, Tao-Tao, Fan, Zu-Sen, Han, Ze-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646347/
https://www.ncbi.nlm.nih.gov/pubmed/26569409
http://dx.doi.org/10.1371/journal.pone.0143042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646347/
https://www.ncbi.nlm.nih.gov/pubmed/26569409
http://dx.doi.org/10.1371/journal.pone.0143042

Ejemplares similares