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Posttranslational Regulation of Human DNA Polymerase ι

Human DNA polymerases (pols) η and ι are Y-family DNA polymerase paralogs that facilitate translesion synthesis past damaged DNA. Both polη and polι can be monoubiquitinated in vivo. Polη has been shown to be ubiquitinated at one primary site. When this site is unavailable, three nearby lysines may...

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Detalles Bibliográficos
Autores principales: McIntyre, Justyna, McLenigan, Mary P., Frank, Ekaterina G., Dai, Xiaoxia, Yang, Wei, Wang, Yinsheng, Woodgate, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646365/
https://www.ncbi.nlm.nih.gov/pubmed/26370087
http://dx.doi.org/10.1074/jbc.M115.675769