GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells

Dyskeratosis congenita is an inherited disease caused by mutations in genes coding for telomeric components. It was previously reported that expression of a dyskerin-derived peptide, GSE24.2, increases telomerase activity, regulates gene expression and decreases DNA damage and oxidative stress in dy...

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Detalles Bibliográficos
Autores principales: Iarriccio, Laura, Manguán-García, Cristina, Pintado-Berninches, Laura, Mancheño, José Miguel, Molina, Antonio, Perona, Rosario, Sastre, Leandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646510/
https://www.ncbi.nlm.nih.gov/pubmed/26571381
http://dx.doi.org/10.1371/journal.pone.0142980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646510/
https://www.ncbi.nlm.nih.gov/pubmed/26571381
http://dx.doi.org/10.1371/journal.pone.0142980

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