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A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb’s Release from 7SK snRNP

The latent reservoirs of HIV represent a major impediment to eradication of HIV/AIDS. To overcome this problem, agents that can activate latent HIV proviruses have been actively sought after, as they can potentially be used in combination with the highly active antiretroviral therapy (HAART) to elim...

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Detalles Bibliográficos
Autores principales: Wang, Cong, Yang, Shuiyuan, Lu, Huasong, You, Hongchao, Ni, Man, Shan, Wenjun, Lin, Ting, Gao, Xiang, Chen, Haifeng, Zhou, Qiang, Xue, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646521/
https://www.ncbi.nlm.nih.gov/pubmed/26569506
http://dx.doi.org/10.1371/journal.pone.0142739