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A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb’s Release from 7SK snRNP
The latent reservoirs of HIV represent a major impediment to eradication of HIV/AIDS. To overcome this problem, agents that can activate latent HIV proviruses have been actively sought after, as they can potentially be used in combination with the highly active antiretroviral therapy (HAART) to elim...
Autores principales: | Wang, Cong, Yang, Shuiyuan, Lu, Huasong, You, Hongchao, Ni, Man, Shan, Wenjun, Lin, Ting, Gao, Xiang, Chen, Haifeng, Zhou, Qiang, Xue, Yuhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646521/ https://www.ncbi.nlm.nih.gov/pubmed/26569506 http://dx.doi.org/10.1371/journal.pone.0142739 |
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