SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance

Alterations in chromatin structure caused by deregulated epigenetic mechanisms collaborate with underlying genetic lesions to promote cancer. SMARCA4/BRG1, a core component of the SWI/SNF ATP-dependent chromatin-remodelling complex, has been implicated by its mutational spectrum as exerting a tumour...

Descripción completa

Detalles Bibliográficos
Autores principales: Cruickshank, V. Adam, Sroczynska, Patrycja, Sankar, Aditya, Miyagi, Satoru, Rundsten, Carsten Friis, Johansen, Jens Vilstrup, Helin, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646637/
https://www.ncbi.nlm.nih.gov/pubmed/26571505
http://dx.doi.org/10.1371/journal.pone.0142806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646637/
https://www.ncbi.nlm.nih.gov/pubmed/26571505
http://dx.doi.org/10.1371/journal.pone.0142806

Ejemplares similares