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Abnormal Protein Glycosylation and Activated PI3K/Akt/mTOR Pathway: Role in Bladder Cancer Prognosis and Targeted Therapeutics

Muscle invasive bladder cancer (MIBC, stage ≥T2) is generally associated with poor prognosis, constituting the second most common cause of death among genitourinary tumours. Due to high molecular heterogeneity significant variations in the natural history and disease outcome have been observed. This...

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Detalles Bibliográficos
Autores principales: Costa, Céu, Pereira, Sofia, Lima, Luís, Peixoto, Andreia, Fernandes, Elisabete, Neves, Diogo, Neves, Manuel, Gaiteiro, Cristiana, Tavares, Ana, Gil da Costa, Rui M., Cruz, Ricardo, Amaro, Teresina, Oliveira, Paula A., Ferreira, José Alexandre, Santos, Lúcio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646664/
https://www.ncbi.nlm.nih.gov/pubmed/26569621
http://dx.doi.org/10.1371/journal.pone.0141253