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Identification of New Antifungal Compounds Targeting Thioredoxin Reductase of Paracoccidioides Genus

The prevalence of invasive fungal infections worldwide has increased in the last decades. The development of specific drugs targeting pathogenic fungi without producing collateral damage to mammalian cells is a daunting pharmacological challenge. Indeed, many of the toxicities and drug interactions...

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Detalles Bibliográficos
Autores principales: Abadio, Ana Karina Rodrigues, Kioshima, Erika Seki, Leroux, Vincent, Martins, Natalia Florêncio, Maigret, Bernard, Felipe, Maria Sueli Soares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646694/
https://www.ncbi.nlm.nih.gov/pubmed/26569405
http://dx.doi.org/10.1371/journal.pone.0142926