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Identification of New Antifungal Compounds Targeting Thioredoxin Reductase of Paracoccidioides Genus
The prevalence of invasive fungal infections worldwide has increased in the last decades. The development of specific drugs targeting pathogenic fungi without producing collateral damage to mammalian cells is a daunting pharmacological challenge. Indeed, many of the toxicities and drug interactions...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646694/ https://www.ncbi.nlm.nih.gov/pubmed/26569405 http://dx.doi.org/10.1371/journal.pone.0142926 |