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Crosslinking of a Peritrophic Matrix Protein Protects Gut Epithelia from Bacterial Exotoxins

Transglutaminase (TG) catalyzes protein-protein crosslinking, which has important and diverse roles in vertebrates and invertebrates. Here we demonstrate that Drosophila TG crosslinks drosocrystallin, a peritrophic matrix protein, to form a stable fiber structure on the gut peritrophic matrix. RNA i...

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Detalles Bibliográficos
Autores principales: Shibata, Toshio, Maki, Kouki, Hadano, Jinki, Fujikawa, Takumi, Kitazaki, Kazuki, Koshiba, Takumi, Kawabata, Shun-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646701/
https://www.ncbi.nlm.nih.gov/pubmed/26506243
http://dx.doi.org/10.1371/journal.ppat.1005244