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Structure of transcribed chromatin is a sensor of DNA damage
Early detection and repair of damaged DNA is essential for cell functioning and survival. Although multiple cellular systems are involved in the repair of single-strand DNA breaks (SSBs), it remains unknown how SSBs present in the nontemplate strand (NT-SSBs) of DNA organized in chromatin are detect...
Autores principales: | Pestov, Nikolay A., Gerasimova, Nadezhda S., Kulaeva, Olga I., Studitsky, Vasily M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646769/ https://www.ncbi.nlm.nih.gov/pubmed/26601207 http://dx.doi.org/10.1126/sciadv.1500021 |
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