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Local variations of HER2 dimerization in breast cancer cells discovered by correlative fluorescence and liquid electron microscopy
The formation of HER2 homodimers plays an important role in breast cancer aggressiveness and progression; however, little is known about its localization. We have studied the intra- and intercellular variation of HER2 at the single-molecule level in intact SKBR3 breast cancer cells. Whole cells were...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646781/ https://www.ncbi.nlm.nih.gov/pubmed/26601217 http://dx.doi.org/10.1126/sciadv.1500165 |