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Local variations of HER2 dimerization in breast cancer cells discovered by correlative fluorescence and liquid electron microscopy

The formation of HER2 homodimers plays an important role in breast cancer aggressiveness and progression; however, little is known about its localization. We have studied the intra- and intercellular variation of HER2 at the single-molecule level in intact SKBR3 breast cancer cells. Whole cells were...

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Detalles Bibliográficos
Autores principales: Peckys, Diana B., Korf, Ulrike, de Jonge, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646781/
https://www.ncbi.nlm.nih.gov/pubmed/26601217
http://dx.doi.org/10.1126/sciadv.1500165