Co-potentiation of antigen recognition: A mechanism to boost weak T cell responses and provide immunotherapy in vivo

Adaptive immunity is mediated by antigen receptors that can induce weak or strong immune responses depending on the nature of the antigen that is bound. In T lymphocytes, antigen recognition triggers signal transduction by clustering T cell receptor (TCR)/CD3 multiprotein complexes. In addition, it...

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Detalles Bibliográficos
Autores principales: Hoffmann, Michele M., Molina-Mendiola, Carlos, Nelson, Alfreda D., Parks, Christopher A., Reyes, Edwin E., Hansen, Michael J., Rajagopalan, Govindarajan, Pease, Larry R., Schrum, Adam G., Gil, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646799/
https://www.ncbi.nlm.nih.gov/pubmed/26601285
http://dx.doi.org/10.1126/sciadv.1500415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646799/
https://www.ncbi.nlm.nih.gov/pubmed/26601285
http://dx.doi.org/10.1126/sciadv.1500415

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