Cargando…

Kinetics of small molecule interactions with membrane proteins in single cells measured with mechanical amplification

Measuring small molecule interactions with membrane proteins in single cells is critical for understanding many cellular processes and for screening drugs. However, developing such a capability has been a difficult challenge. We show that molecular interactions with membrane proteins induce a mechan...

Descripción completa

Detalles Bibliográficos
Autores principales: Guan, Yan, Shan, Xiaonan, Zhang, Fenni, Wang, Shaopeng, Chen, Hong-Yuan, Tao, Nongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646812/
https://www.ncbi.nlm.nih.gov/pubmed/26601298
http://dx.doi.org/10.1126/sciadv.1500633