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UCP2 modulates single-channel properties of a MCU-dependent Ca(2+) inward current in mitochondria

The mitochondrial Ca(2+) uniporter is a highly Ca(2+)-selective protein complex that consists of the pore-forming mitochondrial Ca(2+) uniporter protein (MCU), the scaffolding essential MCU regulator (EMRE), and mitochondrial calcium uptake 1 and 2 (MICU1/2), which negatively regulate mitochondrial...

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Detalles Bibliográficos
Autores principales: Bondarenko, Alexander I., Parichatikanond, Warisara, Madreiter, Corina T., Rost, Rene, Waldeck-Weiermair, Markus, Malli, Roland, Graier, Wolfgang F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646917/
https://www.ncbi.nlm.nih.gov/pubmed/26275882
http://dx.doi.org/10.1007/s00424-015-1727-z