CYP4F18-Deficient Neutrophils Exhibit Increased Chemotaxis to Complement Component C5a

CYP4Fs were first identified as enzymes that catalyze hydroxylation of leukotriene B(4) (LTB(4)). CYP4F18 has an unusual expression in neutrophils and was predicted to play a role in regulating LTB(4)-dependent inflammation. We compared chemotaxis of wild-type and Cyp4f18 knockout neutrophils using...

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Detalles Bibliográficos
Autores principales: Vaivoda, Rachel, Vaine, Christine, Boerstler, Cassandra, Galloway, Kristy, Christmas, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647059/
https://www.ncbi.nlm.nih.gov/pubmed/26613087
http://dx.doi.org/10.1155/2015/250456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647059/
https://www.ncbi.nlm.nih.gov/pubmed/26613087
http://dx.doi.org/10.1155/2015/250456

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