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CYP4F18-Deficient Neutrophils Exhibit Increased Chemotaxis to Complement Component C5a
CYP4Fs were first identified as enzymes that catalyze hydroxylation of leukotriene B(4) (LTB(4)). CYP4F18 has an unusual expression in neutrophils and was predicted to play a role in regulating LTB(4)-dependent inflammation. We compared chemotaxis of wild-type and Cyp4f18 knockout neutrophils using...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647059/ https://www.ncbi.nlm.nih.gov/pubmed/26613087 http://dx.doi.org/10.1155/2015/250456 |