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Optogenetic stimulation reveals distinct modulatory properties of thalamostriatal vs corticostriatal glutamatergic inputs to fast-spiking interneurons

Parvalbumin-containing fast-spiking interneurons (FSIs) exert a powerful feed-forward GABAergic inhibition on striatal medium spiny neurons (MSNs), playing a critical role in timing striatal output. However, how glutamatergic inputs modulate their firing activity is still unexplored. Here, by means...

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Detalles Bibliográficos
Autores principales: Sciamanna, Giuseppe, Ponterio, Giulia, Mandolesi, Georgia, Bonsi, Paola, Pisani, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647205/
https://www.ncbi.nlm.nih.gov/pubmed/26572101
http://dx.doi.org/10.1038/srep16742