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Comparison of the crystal structures of 4,4′-bis­[3-(4-methyl­piperidin-1-yl)prop-1-yn-1-yl]-1,1′-biphenyl and 4,4′-bis­[3-(2,2,6,6-tetra­methyl­piperidin-1-yl)prop-1-yn-1-yl]-1,1′-biphen­yl

As part of a comprehensive program to discover α9α10 nicotinic acetyl­choline receptor antagonists, the title compounds C(30)H(36)N(2), (I), and C(36)H(48)N(2), (II), were synthesized by coupling 4,4′-bis­(3-bromo­prop-1-yn-1-yl)-1,1′-biphenyl with 4-methyl­piperidine and 2,2,6,6-tetra­methyl­piperi...

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Detalles Bibliográficos
Autores principales: Wan, Anqi, Penthala, Narsimha Reddy, Fifer, E. Kim, Parkin, Sean, Crooks, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647388/
https://www.ncbi.nlm.nih.gov/pubmed/26594389
http://dx.doi.org/10.1107/S2056989015015352