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Functional analyses of phosphorylation events in human Argonaute 2

Argonaute 2 (Ago2) protein is a central effector of RNA interference (RNAi) pathways and regulates mammalian genes on a global level. The mechanisms of Ago2-mediated silencing are well understood, but less is known about its regulation. Recent reports indicate that phosphorylation significantly affe...

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Detalles Bibliográficos
Autores principales: Lopez-Orozco, Joaquin, Pare, Justin M., Holme, Andrea L., Chaulk, Steven G., Fahlman, Richard P., Hobman, Tom C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647457/
https://www.ncbi.nlm.nih.gov/pubmed/26443379
http://dx.doi.org/10.1261/rna.053207.115