An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis

N(6)-threonylcarbamoyl-adenosine (t6A) is one of the few RNA modifications that is universally present in life. This modification occurs at high frequency at position 37 of most tRNAs that decode ANN codons, and stabilizes cognate anticodon–codon interactions. Nearly all genetic studies of the t6A p...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Ching-Jung, Smibert, Peter, Zhao, Xiaoyu, Hu, Jennifer F., Ramroop, Johnny, Kellner, Stefanie M., Benton, Matthew A., Govind, Shubha, Dedon, Peter C., Sternglanz, Rolf, Lai, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647464/
https://www.ncbi.nlm.nih.gov/pubmed/26516084
http://dx.doi.org/10.1261/rna.053934.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647464/
https://www.ncbi.nlm.nih.gov/pubmed/26516084
http://dx.doi.org/10.1261/rna.053934.115

Ejemplares similares