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Cetuximab ameliorates suppressive phenotypes of myeloid antigen presenting cells in head and neck cancer patients

BACKGROUND: Myeloid-derived suppressor cells (MDSC) and M2 monocytes/macrophages are two types of suppressive myeloid antigen presenting cells that have been shown to promote tumor progression and correlate with poor prognosis in cancer patients. Tumor antigen specific monoclonal antibodies (mAb) ha...

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Detalles Bibliográficos
Autores principales: Li, Jing, Srivastava, Raghvendra M., Ettyreddy, Abhinav, Ferris, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647471/
https://www.ncbi.nlm.nih.gov/pubmed/26579227
http://dx.doi.org/10.1186/s40425-015-0097-6