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Cetuximab ameliorates suppressive phenotypes of myeloid antigen presenting cells in head and neck cancer patients
BACKGROUND: Myeloid-derived suppressor cells (MDSC) and M2 monocytes/macrophages are two types of suppressive myeloid antigen presenting cells that have been shown to promote tumor progression and correlate with poor prognosis in cancer patients. Tumor antigen specific monoclonal antibodies (mAb) ha...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647471/ https://www.ncbi.nlm.nih.gov/pubmed/26579227 http://dx.doi.org/10.1186/s40425-015-0097-6 |