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The expression level of the transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) determines cellular survival after radiation treatment

BACKGROUND: Tumour hypoxia promotes radioresistance and is associated with poor prognosis. The transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT), also designated as Hypoxia-inducible factor (HIF)-1β, is part of the HIF pathway which mediates cellular adaptations to oxygen de...

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Detalles Bibliográficos
Autores principales: Mandl, Markus, Lieberum, Maria- Katharina, Dunst, Juergen, Depping, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647475/
https://www.ncbi.nlm.nih.gov/pubmed/26572229
http://dx.doi.org/10.1186/s13014-015-0539-9