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The expression level of the transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) determines cellular survival after radiation treatment
BACKGROUND: Tumour hypoxia promotes radioresistance and is associated with poor prognosis. The transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT), also designated as Hypoxia-inducible factor (HIF)-1β, is part of the HIF pathway which mediates cellular adaptations to oxygen de...
Autores principales: | Mandl, Markus, Lieberum, Maria- Katharina, Dunst, Juergen, Depping, Reinhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647475/ https://www.ncbi.nlm.nih.gov/pubmed/26572229 http://dx.doi.org/10.1186/s13014-015-0539-9 |
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